High GGT Level In Your Performance Horse And Significance

Increases in serum GGT activity are primarily indicative of cholestatic liver disease but may result from colonic displacement or the administration of drugs.

Rule of thumb:

1) When GGT, SGOT and CPK are all elevated then rule out extrahepatic cholestasis and intra-hepatic cholestasis

2) When GGT is high and SGOT and CPK are normal then rule out colonic displacement and drug induced drugs such as dexamethasone, prednisone, rifampin, and benzimidazoles.

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